Transregional Collaborative Research Centre 152
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Curriculum Vitae

Advanced Professional Positions

  • 2010 – present, Professor (W2) tenure track, LMU Munich, Walther Straub Institute of Pharmacology and Toxicology, Head: Thomas Gudermann
  • 2008 – 2010 „Außerplanmäßiger (Apl.)“ Professor University of Marburg, Germany, Institute of Pharmacology and Toxicology

Professional Experience and Postdoctoral Training

  • 2000 – 2008 Group Leader, University of Marburg, Germany, Institute of Pharmacology and Toxicology
    Director: Thomas Gudermann
  • 1997 – 2000 Research Fellow, University of California at Los Angeles (UCLA), Los Angeles, USA, Department of Anesthesiology, Head: Lutz Birnbaumer
  • 1994 – 1997 Group Leader, University of Ulm, Institute of Pharmacology and Toxicology, Director: Peter Gierschik
  • 1992 – 1994 Postdoctoral Fellow, German Cancer Research Center Heidelberg, Germany, Department of Molecular Pharmacology, Mentor: Peter Gierschik

Academic Education

  • 2004 Habilitation (Pharmacology), University of Marburg, Germany, Mentor: Thomas Gudermann
  • 1991 Dr. rer. nat., University of Heidelberg, Germany, Mentor: Konrad Beyreuther
  • 1988 Diploma (Biology), University of Heidelberg, Germany, Mentor: Friedrich Marks

Honours, Awards, Scholarships and Other Qualifications

  • 2007 Galenus von Pergamon Award together with Norbert Weißmann (University of Giessen)
  • 1997 – 1999 Research Fellowship of the Deutsche Forschungsgemeinschaft (DFG)

Publications

  • Hofmann K, Fiedler S, Vierkotten S, Weber J, Klee S, Jia J, Zwickenpflug W, Flockerzi V, Storch U, Yildirim AÖ, Gudermann T, Königshoff M, Dietrich A. Classical transient receptor potential (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis. Biochim Biophys Acta 1863: 560-568, 2017.
  • Forst A-L, Olteanu VS, Mollet G, Wlodowski T, Schaefer F, Dietrich A, Reiser J, Gudermann T, Mederos y Schnitzler M, Storch U. Purinergic P2X4 channels are crucial mechanotransducers in podocytes mediating disorganization of the cytoskeleton. J Am Soc Nephrol 27: 848-662, 2016.
  • Camacho Londoño, JE, Tian Q, Hammer K, Camacho Londoño J, Rei J, Oberhofer M, Mannebach S; Mathar I, Philipp S, Tabellion W, Schweda F, Dietrich A, Kästner L, Laufs U, Birnbaumer L, Flockerzi V, Freichel M, Lipp P. A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of cardiac hypertrophy. Eur Heart J 36: 2257-2266, 2015.
  • Kalwa M, Storch U, Demleitner J, Fiedler S, Mayer T, Kannler M, Fahlbusch M, Barth H, Smrcka A, Hildebrandt F, Gudermann T, Dietrich A. Phospholipase C epsilon-induced TRPC6 activation: A common but redundant mechanism in primary podocytes. J Cell Physiol 230:1389-1399, 2015.
  • Griesi-Oliveira K, Acab A, Gupta AR, Sunaga DY, Chailangkarn T, Nicol X, Nunez Y, Walker MF, Murdoch JD, Sanders SJ, Fernandez TV, Ji W, Lifton RP, Vadasz E, Dietrich A, Pradhan D, Song H, Ming G-l, Guoe X, Haddad G, Marchetto MCN, Spitzer N, Passos-Bueno MR, State MW, Muotri AR. Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons. Mol Psychiatry 20: 1350- 1365, 2015.
  • Malczyk M, Veith C, Fuchs B, Hofmann K, Storch U, Schermuly RT, Witzenrath M, Ahlbrecht K, Fecher-Trost C, Flockerzi V, Ghofrani HA, Grimminger F, Seeger W, Gudermann T, Dietrich A*, Weissmann N*. Classical transient receptor potential channel 1 in hypoxia-induced pulmonary hypertension. Am J Respir Crit Care Med 188: 1451-1459, 2013. *shared senior authorship
  • Tauseef M, Knezevic N, Chava KR, Smith M, Sukriti S, Gianaris N, Obukhov AG, Vogel SM, Schraufnagel DE, Dietrich A, Birnbaumer L, Malik AB, Mehta D. TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation. J Exp Med 209:1953-1968, 2012.
  • Weissmann N, Sydykov A, Kalwa H, Storch U, Fuchs B, Mederos y Schnitzler M, Brandes RP, Grimminger F, Meissner M, Freichel M, Offermanns S, Veit F, Pak O, Krause KH, Schermuly RT, Brewer AC, Schmidt HHHW, Seeger W, Shah AM, Gudermann T*, Ghofrani HA & Dietrich A*. Activation of TRPC6 channels is essential for lung ischemia–reperfusion-induced lung edema in mice. Nat Commun 3:649, 2012. *shared senior authorship
  • Tsvilovskyy VV, Zholos AV, Aberle T, Dietrich A, Zhu MX, Birnbaumer L, Freichel M, Flockerzi V. Deletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo. Gastroenterology 137:1415-1424, 2009.
  • Hartmann J, Dragicevic E, Adelsberger H, Henning H, Sumser M, Abramowitz J, Blum R, Dietrich A, Freichel M, Flockerzi V, Birnbaumer L, Konnerth A. TRPC3 channels are required for synaptic transmission and motor coordination. Neuron 59:392-398, 2008.