Transregional Collaborative Research Centre 152
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Curriculum Vitae

Advanced Professional Positions

  • 2012 Clinical director, Department of Cardiology, Klinikum rechts der Isar, TU Munich, Germany
  • 2006 – present, Full Professor (W2), Klinikum rechts der Isar and Deutsches Herzzentrum, TU Munich, Germany
  • 2005 – present Assistant Professor in Medicine, Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, USA (joint appointment)
  • 2000 – present Principal Investigator, Department of Cardiology, Klinikum rechts der Isar and Deutsches Herzzentrum, TU Munich, Germany, Director: Albert Schömig

Professional Experience and Postdoctoral Training

  • 1996 – 2000 Junior Investigator, Department of Cardiology, Klinikum rechts der Isar and Deutsches Herzzentrum, TU Munich, Germany, Director: Albert Schömig

Academic Education

  • 2002 Habilitation (Dr. med. habil. degree), TU Munich
  • 1996 Dr. med., Freie Universität Berlin, Department of Pharmacology, Mentor: Günter Schultz
  • 1988 – 1994 Studies of Medicine, Freie Universität Berlin

Honours, Awards, Scholarships and Other Qualifications

  • 2005 Louis N. Katz Prize of the American Heart Association
  • 2004 Astra-Zeneca Award (Cardiovascular Sciences)
  • 2002-2005 DFG-Heisenberg Scholar at the Institute of Molecular Medicine, University of California San Diego, USA (director: K. Chien)
  • 1998 Merck Sharp Dhome Award (Heart Failure)
  • 1998 Habilitation-Scholarship of the Technische Universität München
  • 1997 Rudolf Buchheim Award, (German Society of Pharmacology and Toxicology)

Professional Activities, Memberships

  • 2006 – present Member of the Harvard Stem Cell Institute (HSCI), Cardiovascular Section, Harvard University, Cambridge, USA

Publications

  • Jung CB, Moretti A, Mederos y Schnitzler M, Iop L, Storch U, Bellin M, Dorn T, Ruppenthal S, Pfeiffer S, Goedel A, Dirschinger RJ, Seyfarth M, Lam JT, Sinnecker D, Gudermann T, Lipp P, Laugwitz KL. Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia. EMBO Mol Med 4:180-191, 2012.
  • Moretti A, Bellin M, Welling A, Jung CB, Lam JT, Bott-Flügel L, Dorn T, Gödel A, Höhnke C, Hofmann F, Seyfarth M, Sinnecker D, Schömig A, Laugwitz KL. Patient-specific induced pluripotent stem cell models for long-QT syndrome. N Engl J Med 363:1397-409, 2010.
  • Moretti A, Bellin M, Jung CB, Thies T, Takashima Y, Bernshausen A, Schiemann M, Fisher S, Moosmang S, Smith AG, Lam JT, Laugwitz KL. Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors. FASEB J 24:700-711, 2010.
  • Moretti A, Caron L, Nakano A, Lam JT, Chen Y, Qyang Y, Sasaki M, Yunfu S, Evans S, Laugwitz KL, Chien KR. Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. Cell 127:1151-1166, 2006.
  • Laugwitz K-L, Moretti A, Lam J, Gruber P, Yinhong Chen, Woodard S, Lin L-Z, Cai C-L, Lu M, Reth M, Platoshyn O, Yuan J, Evans S, Chien KR. Postnatal Isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Nature 433:647-653, 2005.