Transregional Collaborative Research Centre 152
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Curriculum Vitae

Professional Experience and Postdoctoral Training

2009 – present Akademischer Rat, Institute of Physiology, University of Freiburg
2008 Senior scientist, Institute of Physiology, University of Freiburg
2000 – 2002 Postdoctoral fellow, Institute of Physiology, University of Tübingen, Supervisor: Bernd Fakler

Academic Education

  • 1996 – 2000 PhD thesis at the Institute of Physiology (Dr. rer. nat.), University of Tübingen, Mentors: Bernd Fakler / Bernd Hamprecht
  • 1993 – 1994 Biochemistry, Graduate studies, University of California at Riverside, degree: Master of Science
  • 1990 – 1996 Biochemistry, Graduate studies, University of Tübingen, Diploma thesis at the Section of Sensory Biophysics (ENT Hospital), University of Tübingen (Dipl. biochem.), Mentor: Peter Ruppersberg

Honours, Awards, Scholarships and Other Qualifications

  • 1999 Poster award at the American Physiological Society Meeting in Aspen/Colorado, USA
    Professional Activities, Memberships
  • 2012 Board member of the German BioValley e.V.
  • 2011 Responsible Investigator of BIOSS (Centre for biological signalling studies), Freiburg
  • 2010 Member of the SFB 746 (“Functional specificity by coupling and modification of proteins”)
  • 2005 – present, CEO / CSO of Logopharm GmbH (proteomic R&D services), March-Buchheim
  • 2002 – 2005 CEO / CSO of Complexio GmbH (proteomics technology development startup), March-Buchheim

Publications

  • Schmidt N, Kollewe A, Constantin CE, Henrich S, Ritzau-Jost A, Bildl W, Saalbach A, Hallermann S, Kulik A, Fakler B*, Schulte U*. Neuroplastin and basigin are essential auxiliary subunits of plasma membrane Ca2+-ATPases and key regulators of Ca2+ clearance. Neuron 96:827-838, 2017.
  • Castonguay J, Orth JHC, Müller T, Sleman F, Grimm C, Wahl-Schott C, Biel M, Mallmann RT, Bildl W, Schulte U, Klugbauer N. The two-pore channel TPC1 is required for efficient protein processing through early and recycling endosomes. Sci Rep. 7:10038, 2017.
  • Müller CS, Bildl W, Haupt A, Ellenrieder L, Becker T, Hunte C, Fakler B, Schulte U. Cryo-slicing Blue Native-Mass Spectrometry (csBN-MS), a Novel Technology for High Resolution Complexome Profiling. Mol Cell Proteomics 15:669-681, 2016.
  • Schwenk J, Baehrens D, Haupt A, Bildl W, Boudkkazi S, Roeper J, Fakler B*, Schulte U*. Regional diversity and developmental dynamics of the AMPA-receptor proteome in the mammalian brain. Neuron. 84:41-54, 2014.
  • Duncker SV, Franz C, Kuhn S, Schulte U, Campanelli D, Brandt N, Hirt B, Fakler B, Blin N, Ruth P, Engel J, Marcotti W, Zimmermann U, Knipper M. Otoferlin couples to clathrin-mediated endocytosis in mature cochlear inner hair cells. J Neurosci. 33:9508-9519, 2013.
  • Jeworutzki E, López-Hernández T, Capdevila-Nortes X, Sirisi S, Bengtsson L, Montolio M, Zifarelli G, Arnedo T, Müller CS, Schulte U, Nunes V, Martínez A, Jentsch TJ, Gasull X, Pusch M, Estévez R. GlialCAM, a Protein Defective in a Leukodystrophy, Serves as a ClC-2 Cl− Channel Auxiliary Subunit. Neuron. 73:951-961, 2012.
  • Bildl W, Haupt A, Mueller CS, Biniossek ML, Thumfart JO, Hueber B, Fakler B, Schulte U. Extending The Dynamic Range Of Label-Free Mass Spectrometric Quantification Of Affinity Purifications. Mol Cell Proteomics 11:M111.007955. doi: 10.1074/mcp.M111.007955, 2012.
  • Schwenk J, Harmel N, Brechet A, Zolles G, Berkefeld H, Muller CS, Bildl W, Baehrens D, Huber B, Kulik A, Klöcker N, Schulte U*, Fakler B*. High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes. Neuron 74:621-633, 2012.
  • Müller CS, Haupt A, Bildl W, Schindler J, Knaus HG, Meissner, M Rammner B, Striessnig J, Flockerzi V, Fakler B, Schulte U. Feature Article: Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain. Proc Natl Acad Sci USA 107:14950-14957, 2011.
  • Schwenk J, Metz M, Zolles G, Turecek R, Bildl W, Tarusawa E, Kulik A, Unger A, Tiao JY, Ivankova K, Seddik R, Gassmann M, Schulte U, Fakler B, Bettler B. Native GABAB receptors are heteromultimers with a family of auxiliary subunits. Nature 465:231-235, 2010.
    *shared senior authorship