Transregional Collaborative Research Centre 152
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Curriculum Vitae

Advanced Professional Positions

  • since 2017 Deputy Chair of the Biomedical Center of the LMU Munich
  • since 2013 Full professor (W3) and Director of the Institute of Clinical Neuroimmunology,
    University Hospital and Biomedical Center of the LMU Munich
  • 2008 - 2013 Associate Professor (W2) for Translational Neuroimmunology, Institute of
    Clinical Neuroimmunology, University Hospital and Biomedical Center
    of the LMU Munich
  • 2005 – 2008 Group leader funded by the Emmy Noether-Program of the
    German Research Foundation (DFG), Institute of Clinical Neuroimmunology,
    University Hospital LMU Munich

Professional Experience and Postdoctoral Training

  • 2004 - 2005 Research Associate in the Department of Molecular and Cellular Biology
    (Lab of Prof. J. Lichtman), Harvard University, Cambridge, USA
  • 2003 – 2004 Research Associate in the Department of Anatomy and Neurobiology
    (Lab of Prof. J. Lichtman), Washington University School of Medicine, St. Louis
  • 2001 – 2003 Post-doctoral fellow in the Department of Neuromorphology
    (director: Prof. M. Schwab), Brain Research Institute, University and ETH Zurich
  • 1999 – 2001 Residency training in Neurology, University Hospital LMU Munich

Academic Education

  • 1994 – 1999 MD thesis at the Department of Neuroimmunology (director: Prof. H. Wekerle),
    Max-Planck-Institute of Neurobiology, Martinsried; Grade: summa cum laude
  • 1992 – 1999 Medical Studies at the RWTH Aachen and the LMU Munich

Honours, Awards, Scholarships and Other Qualifications

  • 2020 Elected member of the German National Academy of Sciences (Leopoldina)
  • 2012 ERC Consolidator Grant awarded by the European Research Council
  • 2008 “Habilitationsförderpreis“ of LMU Munich
  • 2004 1st Wyeth Award for MS Research presented by the
    German Neurological Society
  • 2004 1st Junior Research Award of the German Multiple Sclerosis Society
    (“Sobek Price“)
  • 1994-1999 Scholar of the German National Scholarship Foundation
    Freiburg
Professional Activities, Memberships
  • since 2020 Deputy Speaker of the Collaborative Research Center SFB-TRR 274
    “Checkpoints of CNS recovery”
  • since 2020 Head of the Examination Board, Elite Master Program
    “Human Biology –Principles of Health and Disease”, LMU Munich
  • since 2016 Board Member of the Clinical Competence Network “Multiple Sclerosis”
  • since 2016 Board Member of the Collaborative Research Center SFB-TRR 128
    “Multiple Sclerosis –Initiating/effector vs. regulatory mechanisms”
  • since 2012 Board Member and Research Focus Coordinator of the Excellence Cluster
    “Munich Cluster for Systems Neurology (SyNergy)”

Publications

  • Jafari M, Schumacher AM, Snaidero N, Ullrich Gavilanes EM, Neziraj T, Kocsis-Jutka V, Engels D, Jürgens T, Wagner I, Weidinger JDF, Schmidt SS, Beltrán E, Hagan N, Woodworth L, Ofengeim D, Gans J, Wolf F, Kreutzfeldt M, Portugues R, Merkler D, Misgeld T, Kerschensteiner M: Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation. Nat Neurosci 24:355-367, 2021.
  • Snaidero N, Schifferer M, Mezydlo A, Zalc B, Kerschensteiner M*, Misgeld T*: Myelin replacement triggered by single-cell demyelination in mouse cortex. Nat Commun 11:4901, 2020.
  • Witte ME, Schumacher AMS, Mahler CF, Bewersdorf JP, Lehmitz J, Scheiter A, Sánchez P, Williams PR, Griesbeck O, Naumann R, Misgeld T, Kerschensteiner M: Calcium influx through plasma-membrane nanoruptures drives axon degeneration in a model of multiple sclerosis. Neuron 101:615-624, 2019.
  • Locatelli G, Theodorou D, Kendirli A, Jordᾶo MJC, Staszewski O, Phulphagar K, Cantuti-Castelvetri L, Dagkalis A, Bessis A, Simons M, Meissner F, Prinz M, Kerschensteiner M: Mononuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model. Nat Neurosci 21:1196-120, 2018.
  • Romanelli E, Merkler D, Mezydlo A, Weil MT, Weber MS, Nikić I, Potz S, Meinl E, Matznick FE, Kreutzfeldt M, Ghanem A, Conzelmann KK, Metz I, Brück W, Routh M, Simons M, Bishop D, Misgeld T, Kerschensteiner M: Myelinosome formation represents an early stage of oligodendrocyte damage in multiple sclerosis and its animal model. Nat Commun 7:13275, 2016.
  • Sorbara CD, Wagner NE, Ladwig A, Nikić I, Merkler D, Kleele T, Marinković P, Naumann R, Godinho L, Bareyre FM, Bishop D, Misgeld T, Kerschensteiner M: Pervasive axonal transport deficits in multiple sclerosis models. Neuron 84:1183-90, 2014.
  • Williams PR, Marincu BN, Sorbara CD, Mahler CF, Schumacher AM, Griesbeck O, Kerschensteiner M*, Misgeld T*: A recoverable state of axon injury persists for hours after spinal cord contusion in vivo.
    Nat Commun 5:5683, 2014.
  • Breckwoldt MO, Pfister FM, Bradley PM, Marinković P, Williams PR, Brill MS, Plomer B, Schmalz A, St Clair DK, Naumann R, Griesbeck O, Schwarzländer M, Godinho L, Bareyre FM, Dick TP, Kerschensteiner M*, Misgeld T*: Multiparametric optical analysis of mitochondrial redox signals during neuronal physiology and pathology in vivo. Nat Med 20:555-60, 2014.
  • Bishop D, Nikić I, Brinkoetter M, Knecht S, Potz S, Kerschensteiner M*, Misgeld T*: Near-infrared branding efficiently correlates light and electron microscopy. Nature Methods 8:568-70, 2011.
  • Nikic I, Merkler D, Sorbara C, Brinkoetter M, Kreutzfeld M, Bareyre FM, Brück W, Bishop D, Misgeld T, Kerschensteiner M: A reversible form of axon damage in multiple sclerosis and its animal model.
    Nat Med 17: 495-9, 2011.
    *Co-senior author and corresponding author