Transregional Collaborative Research Centre 152
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Curriculum Vitae

Professional Experience and Postdoctoral Training

  • since 2018 Group leader, Walther Straub Institute of Pharmacology and Toxicology,
    LMU Munich
  • 2015 – 2018 Postdoctoral Fellow, Institute of Pediatric Endocrinology,
    Charité Universitätsmedizin Berlin

Academic Education

  • 2012 – 2015 Dr. rer. medic. in Biology, Department of Ophtalmolgy,
    Charité Universitätsmedizin Berlin
  • 2005 – 2008 Studies of Anatomy, Isfahan University of Medical Sciences, Isfahan, Iran

Honours, Awards, Scholarships and Other Qualifications

  • 2016 Robert Koch Preis, Charité, Berlin
  • 2011 ENDO 2016 Presidential Prize for the category
    “Insulin Signaling/Insulin Action and Pathopathology of Diabetes”, Boston, USA
    Freiburg

Publications

  • Jacobi S, Khajavi N, Kleinau G, Teumer A, Scheerer P, Homuth G, Völzke H, Wiegand S, Kühnen P, Krude H, Gong M, Raile K, Biebermann H: Evaluation of a rare glucose-dependent insulinotropic polypeptide receptor variant in a patient with disturbed glucose homeostasis. Diabetes, Obes Metab 21:1168-1176, 2019.
  • Bräunig J, Mergler S, Jyrch S, Hoefig CS, Rosowski M, Mittag J, Biebermann H, Khajavi N: 3-Iodothyronamine Activates a Set of Membrane Proteins in Murine Hypothalamic Cell Lines. Front Endocrinol 9:523, 2018.
  • Khajavi N, Finan B, Kluth O, Müller TD, Mergler S, Schulz A, Kleinau G, Scheerer P, Schürmann A, Gudermann T, Tschöp MH, Krude H, DiMarchi RD, Biebermann H: An incretin-based tri-agonist promotes superior insulin secretion from murine pancreatic islets via PLC activation. Cell Signal 51:13-22, 2018.
  • Fischer J, Kleinau G, Rutz C, Zwanziger D, Khajavi N, Müller A, Rehders M, Brix K, Worth C, Führer D, Krude H, Wiesner B, Schülein R, Biebermann H: Evidence of G-protein-coupled receptor and substrate transporter heteromerization at a single molecule level. Cell Mol Life Sci 75:2227-2239, 2018.
  • Khajavi N, Biebermann H, Tschöp M, DiMarchi R. Treatment of diabetes and obesity by rationally designed peptide agonists functioning at multiple metabolic receptors. Developmental Biology of Gastrointestinal Hormones. Endocr Dev 32:165-182, 2017.
  • Buonocore F, Kühnen P, Suntharalingham JP, Del Valle I, Digweed M, Stachelscheid H, Khajavi N, Didi M, Brady AF, Blankenstein O, Procter AM, Dimitri P, Wales JKH, Ghirri P, Knöbl D, Strahm B, Erlacher M, Wlodarski MW, Chen W, Kokai GK, Anderson G, Morrogh D, Moulding DA, McKee SA, Niemeyer CM, Grüters A, Achermann JC: Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans. J Clin Invest 127:1700-1713, 2017.
  • Skrzypski M, Billert M, Mergler S, Khajavi N, Nowak KW, Strowski MZ: Role of TRPV channels in regulating various pancreatic β-cell functions: Lessons from in vitro studies. Biosci Trends 11:9-15, 2017.
  • Skrzypski M, Khajavi N, Mergler S, Billert M, Szczepankiewicz D, Wojciechowicz T, Nowak KW, Strowski MZ: Orexin A modulates INS-1E cell proliferation and insulin secretion via extracellular signal-regulated kinase and transient receptor potential channels. J Physiol Pharmacol 67:643-652, 2016.
  • Khajavi N, Reinach PS, Slavi N, Skrzypski M, Lucius A, Strauß O, Köhrle J, Mergler S: Thyronamine induces TRPM8 channel activation in human conjunctival epithelial cells. Cell Signal 27:315-25, 2015.
    10. Khajavi N, Reinach PS, Skrzypski M, Lude A, Mergler S: L-Carnitine reduces in human conjunctival epithelial cells hypertonic-induced shrinkage through interacting with TRPV1 channels. Cell Physiol Biochem 34:790-803, 2014.