Advanced Professional Positions
- 2001 – present Full Professor (C3) for Neurophysiology, Saarland University, Institute for Physiology
Professional Experience and Postdoctoral Training
- 1997 – 2001 Junior-Group leader, MPI for Biophysical Chemistry, Dept. Neurobiology, Göttingen, Director: Prof. Dr. R. Jahn
- 1993 – 1997 Postdoctoral Fellow, Howard Hughes Medical Inst., Yale University, School of Medicine, New Haven, CT, USA
- 1993 Dr. rer. nat., Biology, University of Tübingen, Doctoral thesis in Neurophysiology, MPI of Psychiatry, Martinsried, Mentor: H. D. Lux
- 1990 Diploma in Biology, University of Tübingen, Diploma thesis at the MPI of Psychiatry, Dept. of Neurobiology, Marinsried, Director: Prof. Dr. H.D. Lux
- 1983 – 1989 Studies of Biology at the University of Tübingen
Honours, Awards, Scholarships and Other Qualifications
- 2006 – present “Ombudsmann” of the Medical faculty
- 1994 Stipend of the Max-Planck-Society (Otto Hahn Medal)
Professional Activities, Memberships
- 2015 – 2020 Member of the SPP1757 (together with Y. Schwarz)
- 2013 – 2020 Member of the CRC1027, C5 , Homburg (together with R. Mohrmann)
- 2011 – 2018 Member of the CRC894, TPA11, Homburg
- 2006 – present Chairman of the Graduate School GK1326 „Calcium Signaling and Cellular Nanodomains“
- 2006 – present Member of the Research committee at the Medical faculty (HOMFOR)
- 2002 – 2007 Member of the GK377, Homburg
- 2001 – 2011 Member of the CRC530, TPC10, Homburg
- 1997 – 2001 Member of the CRC406, TPB8, Göttingen
- Schwarz Y, Zhao N, Kirchhoff F and Bruns D. Astrocytes control synaptic strength by two distinct v-SNARE-dependent release pathways. Nat Neurosci, DOI:10.1038/nn.4647, 2017.
- Bröker-Lai J, Kollewe A*, Schindeldecker B*, Pohle J*, Nguyen Chi V*, Mathar I, Guzman R, Schwarz Y, Lai A, Weißgerber P, Schwegler H, Dietrich A, Both M, Sprengel R, Draguhn A, Köhr G, Fakler B, Flockerzi V, Bruns D, Freichel M. Heteromeric channels from TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory. EMBO J 36:2770-2789, 2017. *contributed equally
- Dhara M*, Yarzagaray A*, Schwarz Y, Makke M, Schindeldecker B, Shaaban A, Böckmann R, Sharma S, Lindau M, Mohrmann R, Bruns D. SNARE TMDs function as catalysts for membrane fusion. Elife doi: 10.7554/eLife.17571, 2016. *contributed equally
- Dhara M, Yarzagaray A, Schwarz Y, Dutta S, Grabner C, Kamali Moghadam P, Bost A, Schirra C, Rettig J, Reim K, Brose N, Mohrmann R, Bruns D. The functional interplay of Complexin II and Synaptotagmin I in exocytosis. J Cell Biol 204: 1123-1140, 2014.
- Borisovska M, Schwarz YN, Dhara M, Yarzagaray A, Hugo S, Narzi D, Siu SWI, Kesavan J, Mohrmann R, Böckmann RA, Bruns D. Membrane-proximal tryptophans of synaptobrevin II stabilize priming of secretory vesicles. J Neurosci 32:15983-15997, 2012.
- Guzman RE, Schwarz IN, Rettig J, Bruns D. SNARE force synchronizes synaptic vesicle fusion and controls the kinetics of quantal synaptic transmission. J Neurosci 30, 10272-10281, 2010.
- Kesavan J, Borisovska M, Bruns D. v-SNARE actions during Ca2+-triggered exocytosis. Cell 131: 351-363, 2007.
- Borisovska M, Zhao Y, Tsytsyura Y, Glyvuk N, Takamori S, Matti U, Rettig J, Südhof T, Bruns D. v-SNAREs control exocytosis from priming to fusion. EMBO J 24: 2114-2126, 2005.
- Bruns D, Jahn R. Real-time measurement of transmitter release from single synaptic vesicles. Nature 377:62-65, 1995.