Transregional Collaborative Research Centre 152
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Curriculum Vitae

Advanced Professional Positions

  • 2008 – present, Group Leader, LMU Munich, Walther Straub Institute of Pharmacology and Toxicology, Head: Thomas Gudermann

Professional Experience and Postdoctoral Training

  • 2000 – 2008 Postdoctoral Fellow, University of Marburg, Institute for Pharmacology and Toxicology,
    Head: Prof. Thomas Gudermann

Academic Education

  • 1999 PhD in Biochemistry, Dept. of Biochemistry, Belarusian State University, Minsk, Belarus, Mentor: Prof. Mikhail Sholukh
  • 1993 Diploma in Biology, Dept. of Biochemistry, Belarusian State University, Minsk, Belarus,
    Mentor: Prof. Mikhail Sholukh

Honours, Awards, Scholarships and Other Qualifications

  • 1999 – 2000 DAAD Research Fellow with Prof. Günter Schultz and Prof. Thomas Gudermann, Institute for Pharmacology, FU Berlin, Germany
  • 1997 Research grant for Young investigators of the Belarus Foundation for fundamental research (M96-018)
  • 1995 PhD fellowship of the Cabinet of Ministers of Belarus
  • 1994 Award of the Belarus Ministry of Science and Education for the Best Student Research Work

Publications

  • Romagnani A, Vettore V, Rezzonico-Jost T, Hampe S, Rottoli E, Nadolni W, Perotti M, Meier MM, Hermanns C, Geiger S, Wennemuth G, Recordati C, Matsushita M, Muehlich S, Proietti M, Chubanov V, Gudermann T, Grassi F, Zierler S. TRPM7 kinase activity is essential for T cell colonization and alloreactivity in the gut. Nat Commun 2017, in press.
  • Ferioli S, Zierler S, Schredelseker J, Gudermann T, Chubanov V. TRPM6 and TRPM7 differentially contribute to the relief of heteromeric TRPM6/7 channels from inhibition by cytosolic Mg2+ and Mg·ATP. Sci Rep 7:8806, 2017.
  • Chubanov V*, Ferioli S, Wisnowsky A, Simmons DG, Leitzinger C, Einer C, Jonas W, Shymkiv Y, Bartsch H, Braun A, Akdogan B, Mittermeier L, Sytik L, Torben F, Jurinovic V, van der Vorst EP, Weber C, Yildirim ÖA, Sotlar K, Schürmann A, Zierler S, Zischka H, Ryazanov AG, Gudermann T*. Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival. Elife 5, 2016. *senior authors
  • Stritt S, Nurden P, Favier R, Favier M, Ferioli S, Gotru SK, Eeuwijk JM, Schulze H, Nurden AT, Lambert MP, Turro E, Burger-Stritt S, Matsushita M, Mittermeier L, Ballerini P, Zierler S, Laffan MA, Chubanov V, Gudermann T, Nieswandt B, Braun A. Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg2+ homeostasis and cytoskeletal architecture. Nat Commun 7: 11097, 2016.
  • Deckmanna K, Filipskia K., Krasteva-Christa G, Froniusc M, Althausd M, Rafiqa A, Papadakisa T, Rennoa L, Jurastowa I, Wesselsa L, Wolffa M, Schütze B, Weiheb E, Chubanov V, Gudermann T, Kleing J, Bschleipferh T, Kummer W. Bitter triggers acetylcholine release from polymodal urethral chemosensory cells and bladder reflexes Proc Natl Acad Sci U S A 111: 8287-92, 2014.
  • Chubanov V*, Mederos y Schnitzler M, Meißner M, Schäfer S, Abstiens K, Hofmann T, Gudermann T*. Natural and synthetic modulators of SK (Kca2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7. Br J Pharmacol 166:1357-76, 2012. *senior authors
  • Mederos y Schnitzler M, Waring J, Gudermann T, and Chubanov V. Evolutionary determinants of divergent calcium selectivity of TRPM channels. FASEB J 22:1540-1551, 2008.
  • Chubanov V, Schlingmann KP, Waring J, Heinzinger J, Kaske S, Waldegger S, Mederos y Schnitzler M, Gudermann T. Hypomagnesemia with secondary hypocalcemia due to a missense mutation in the putative pore-forming region of TRPM6. J Biol Chem 282:7656-7667, 2007.
  • Chubanov V, Waldegger S, Mederos y Schnitzler M, Vitzthum H, Sassen MC, Seyberth HW, Konrad M, and Gudermann T. Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia. Proc Natl Acad Sci USA 101:2894-2899, 2004.
  • Hofmann T, Chubanov V, Gudermann T, and Montell C. TRPM5 is a voltage-modulated and Ca2+-activated monovalent selective cation channel. Curr Biol 13: 1153-8, 2003.