Transregional Collaborative Research Centre 152
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Curriculum Vitae

Advanced Professional Position

  • 2008 – present Professor of Pharmacology and Toxicology (W3) at the Saarland University, Homburg
  • 1998 – 2007 Professor of Pharmacology and Toxicology (C4) at the Saarland University, Homburg
  • 1993 – 1997 Professor of Pharmacology and Toxicology (C4) at the Heidelberg University
  • 1991 – 1992 Professor of Pharmacology and Toxicology (C3) at the TU Munich

Professional Experience and Postdoctoral Training

  • 1988 – 1990 Junior Investigator Department of Biochemistry, Saarland University, Homburg
  • 1986 – 1987 Postdoctoral Fellow Department of Medical Chemistry and Molecular Genetics, Kyoto University, Japan, Mentor: Shosaku Numa
  • 1985 – 1986 Postdoctoral Fellow Department of Biochemistry, Saarland University, Homburg, Mentor: Franz Hofmann
  • 1981 – 1985 Postdoctoral Fellow Department of Pharmacology, Ruprecht-Karls-University, Heidelberg, Mentor: Franz Hofmann

Academic Education

  • 1993 Boards in Pharmacology and Toxicology
  • 1988 Habilitation (Biochemistry), Medical Faculty, Saarland University
  • 1980 Medical Degree, Ruprechts-Karls-University, Heidelberg, Mentor: Franz Hofmann
  • 1980 ECFMG certificate and license to practice medicine
  • 1973 – 1980 Heidelberg University Medical School

Honours, Awards, Scholarships and Other Qualifications

  • 2009 Award of the Feldberg Foundation for Anglo-German Scientific Exchange
  • 2003 Elected member of Leopoldina Nationale Akademie der Wissenschaften
  • 1991 – 2007 Offers of Full Professorship of the Universities of Berlin, Marburg, Auckland, Freiburg
  • 1986 – 1987 Feodor Lynen-Research Fellowship (Alexander von Humboldt Foundation) and Fellowship of the Japan Society of the Promotion of Science: Department of Medical Chemistry and Molecular Genetics, University Kyoto, Japan (Mentor: Shosaku Numa)

Publications

  • Vaeth M, Yang J, Yamashita M, Zee I, Eckstein M, Knosp C, Kaufmann U, Jani P, Lacruz R, Flockerzi V, Kacskovics I, Prakriya M, Feske S. ORAI2 modulates store-operated calcium entry and T cell-mediated immunity. Nat Commun 8: 14714, doi:10.1038/ncomms14714, 2017.
  • Katiyar R, Weissgerber P, Roth E, Dörr J, Sothilingam V, Garcia Garrido M, Beck SC, Seeliger MW, Beck, A, Schmitz F, Flockerzi V. Influence of the β2-subunit of L-type voltage-gated Cav channels on the structural and functional development of photoreceptor ribbon synapses. Investigative Ophthalmology & Visual Science 56, 2312–2324, 2015.
  • Beck A, Speicher T, Stoerger C, Sell T, Dettmer V, Jusoh SA, Abdulmughni A, Cavalié A, Philipp SE, Zhu MX, Helms V, Wissenbach U, Flockerzi V. Conserved Gating Elements in TRPC4 and TRPC5 Channels. J Biol Chem 288, 19471-19483, 2013.
  • Fecher-Trost C, Wissenbach U, Beck A, Schalkowsky P, Stoerger C, Doerr J, Dembek A, Simon-Thomas M, Weber A, Wollenberg P, Ruppert T, Middendorff R, Maurer HH, Flockerzi V. The in vivo TRPV6 protein starts at a non-AUG triplet decoded as methionine upstream the canonical initiation at AUG. J Biol Chem 288, 16629-16644, 2013.
  • Meissner M, Weißgerber P, Camacho Londoño JE, Prenen J, Link S, Ruppenthal S, Molkentin JD, Lipp P, Nilius B, Freichel M, Flockerzi V. Moderate calcium channel dysfunction in adult mice with inducible cardiomyocyte -specific excision of the cacnb2 gene. J Biol Chem 286, 15875-15882, 2011.
  • Link S, Meissner M, Held B, Beck A, Weissgerber P, Freichel M, Flockerzi V. Diversity and developmental expression of L-type calcium channel 2 proteins and their influence on calcium current in murine heart. J Biol Chem 284:30129-30137, 2009.
  • Tsvilovskyy VV, Zholos AV, Aberle T, Philipp SE, Dietrich A, Zhu MX, Birnbaumer L, Freichel M, Flockerzi V. deletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo. Gastroenterology 137, 1415-1424, 2009.
  • Gross SA, Wissenbach U, Philipp SE, Freichel M, Cavalié A, Flockerzi V. Murine ORAI2 splice variants form functional CRAC channels. J Biol Chem 282, 19375-19384, 2007.
  • Berggren P-O, Yang S-N, Murakami M, Efanov AM, Uhles S, Köhler M, Moede T, Fernström A, Appelskog IB, Aspinwall CA, Zaitsev SV, Larsson O, Moitoso de Vargas L, Fecher-Trost C, Weissgerber P, Ludwig A, Leibiger B, Juntti-Berggren L, Barker CJ, Gromada J, Freichel M, Leibiger IB and Flockerzi V. Removal of Ca2+ channel β3 subunit enhances Ca2+-oscillation frequency and insulin exocytosis. Cell 119, 273-284, 2004.
  • Montell C, Birnbaumer L and Flockerzi V. The TRP channels, a remarkable functional family. Cell 108, 595-598, 2002.