Transregional Collaborative Research Centre 152

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Curriculum Vitae

Advanced Professional Positions

2006 – present Group leader, Cardiology Division, First Department of Medicine, Klinikum rechts der Isar
TU Munich, Germany

Professional Experience and Postdoctoral Training

  • 2005 – 2008 Instructor in Medicine, Cardiovascular Research Center, Massachusetts General Hospital,
    Harvard Medical School, Boston, USA, Director: Kenneth R. Chien
  • 2002 – 2005 Project scientist, Institute of Molecular Medicine, University of California San Diego, USA,
    Director: Kenneth R. Chien
  • 1997 – 2002 Postdoctoral Fellow, Cardiology Division, First Department of Medicine, Klinikum rechts der Isar, TU Munich, Germany, Director: Albert Schömig

Academic Education

  • 1997 PhD thesis (Pharmacology and Toxicology), Dept. of Biomedical and Experimental Sciences, University of Padua, Padua, Italy, Mentor: Daniela Pietrobon
  • 1992 Diploma (Chemistry and Pharmaceutical Sciences), Dept. of Pharmacology, University of Padua, Padua, Italy, Mentor: Giuliana Fassina

Honours, Awards, Scholarships and Other Qualifications

  • 2013 Innovationspreises der Deutschen Hochschulmedizin e.V.
  • 2012 Göttingen Academy of Sciences Award for Biology
  • 1998 Astra-Zeneca Award for Young Investigators in Cardiovascular Science
  • 1993 Boards in Pharmacy
  • 1992 Research award for young scientists (Bracco Companies)

Professional Activities, Memberships

  • 2013-present PI member of the Oxbridge Centre for Regenerative Medicine Program of the Wellcome Trust and the British Heart Foundation
  • 2010-present PI member of the Munich Heart Alliance and the German Center for Cardiovascular Research (DZHK)
  • 2010-present Member of the International Society for Stem Cell Research (ISSCR)


  • Bellin M, Casini S, Davis RP, D'Aniello C, Haas J, Ward-van Oostwaard D, Tertoolen LGJ, Jung CB, Elliott DA, Welling A, Laugwitz KL, Moretti A & Mummery CL. Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome. EMBO J (2013) 10.1038/emboj.2013.240
  • Zhang H, Zou B, Yu H, Moretti A, Wang X, Yan W, Babcock JJ, Bellin M, McManus OB, Tomaselli G, Nan F, Laugwitz K-L & Li M. Modulation of hERG potassium channel gating normalizes action potential duration prolonged by dysfunctional KCNQ1 potassium channel. Proc Natl Acad Sci USA, 109:11866–11871, 2012.
  • Jung CB*, Moretti A, Mederos y Schnitzler M, Iop L, Storch U, Bellin M, Dorn T, Ruppenthal S, Pfeiffer S, Goedel A, Dirschinger RJ, Seyfarth M, Lam JT, Sinnecker D, Gudermann T, Lipp P & Laugwitz KL: Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia. EMBO Mol Med 4:180-191, 2012.
  • Moretti A, Bellin M, Welling A, Jung CB, Lam JT, Bott-Flügel L, Dorn T, Gödel A, Höhnke C, Hofmann F, Seyfarth M, Sinnecker D, Schömig A & Laugwitz K-L. Patient-specific induced pluripotent stem cell models for long-QT syndrome. N Engl J Med 363:1397-409, 2010.
  • Qyang Y, Martin-Puig S, Chiravuri M, Chen S, Xu H, Bu L, Jiang X, Lin L, Granger A, Moretti A, Caron L, Wu X, Clarke J, Taketo MM, Laugwitz K-L, Moon RT, Gruber P, Evans SM, Ding S & Chien KR. The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/-catenin pathway. Cell Stem Cell 1:1-15, 2007.