Transregional Collaborative Research Centre 152

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Curriculum Vitae

Advanced Professional Positions

  • 2018 Professor for Neurophysiology, Medizinische Hochschule Hannover
  • 2012 Professor for Molecular Pharmacology, W2 tenure, Department of Pharmacy, LMU Munich
  • 2007 Professor for Molecular Pharmacology, W2 tenure track, Department of Pharmacy, LMU Munich

Professional Experience and Postdoctoral Training

  • 2000 – 2007 Research Assistant, Department of Pharmacy, Pharmacology, LMU Munich, Advisor: Martin Biel,
  • Head of Dept: Martin Biel
  • 1999 – 2000 Research Assistant, Department of Medicine I, Medical School, LMU Munich, Advisor: G. Steinbeck,
  • Head of Dept: G. Steinbeck

Academic Education

  • 2007 Habilitation (Pharmacology), LMU Munich, Mentor: Martin Biel
  • 2000 Approbation in Medicine
  • 1995 – 1997 Dr. med., Albert-Ludwigs-University Freiburg, Mentor: Klaus Starke
  • 1991 – 1998 Study of Medicine, Albert-Ludwigs-University Freiburg and Ruprecht-Karls-University, Heidelberg

 Honours, Awards, Scholarships and Other Qualifications

  • 2016 Call to chair position for Neurophysiology, Medizinische Hochschule Hannover
  • 2016 LMU Lehrinnovationspreis
  • 2016 Innovationspreis Klinische Pharmazie (Sanofi)
  • 2011 Phoenix Pharmazie Wissenschaftspreis
  • 2007 Phoenix Pharmazie Wissenschaftspreis


  • Chao Y, Schludi V, Chen CC, Butz E, Nguyen OP, Müller M, Krüger J, Kammerbauer C, Ben-Johny M, Vollmar A, Berking C, Biel M, Wahl-Schott C #, Grimm C #. TPC2 polymorphisms associated with a hair pigmentation phenotype in humans result in gain of channel function by independent mechanisms. Proc Natl Acad Sci USA 114:E8595-E8602, 2017.
  • Chen CC, Chunlei C, Fenske S, Butz E, Chao YK, Biel M, Ren D, Wahl-Schott C #, Grimm C#. Patch clamp technique to characterize ion channels in individual intact endolysosomes. Nat Protoc 12:1639-1658, 2017.
  • Koch SF, Duong JK, Hsu CW, Tsai YT, Lin CS, Wahl-Schott CA, Tsang SH. Genetic rescue models refute nonautonomous rod cell death in retinitis pigmentosa. Proc Natl Acad Sci USA 114:5259-5264, 2017.
  • Butz ES, Ben-Johny M#, Shen M, Yang PS, Sang L, Biel M, Yue DT, Wahl-Schott C#. Quantifying macromolecular interactions in living cells using FRET two-hybrid assays. Nat Protoc 11:2470-2498, 2016.
  • Fenske S, Pröbstle R, Auer F, Hassan S, Marks V, Pauza DH, Biel M, Wahl-Schott C. Comprehensive Multi-level in vivo and in vitro Analysis of Heart Rate Fluctuations in Mice by ECG Telemetry and Electrophysiology. Nat Protoc 11:61-86, 2016.
  • Sakurai Y, Kolokoltsov AA, Chen CC, Tidwell MW, Bauta WE, Klugbauer N, Grimm C, Wahl-Schott C, Biel M, Davey RA. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment. Science 347:995-8, 2015.
  • Grimm C, Holdt LM, Chen CC, Hassan S, Muller C, Jors S, Cuny H, Kissing S, Schroder B, Butz E, Northoff B, Castonguay J, Luber CA, Moser M, Spahn S, Lullmann-Rauch R, Fendel C, Klugbauer N, Griesbeck O, Haas A, Mann M, Bracher F, Teupser D, Saftig P, Biel M, Wahl-Schott C. High susceptibility to fatty liver disease in two-pore channel 2-deficient mice. Nat Commun 5:4699, 2014.
  • Chen CC, Keller M, Hess M, Schiffmann R, Urban N, Wolfgardt A, Schaefer M, Bracher F, Biel M, Wahl-Schott C, Grimm C. A small molecule restores function to TRPML1 mutant isoforms responsible for mucolipidosis type IV. Nat Commun 5:4681, 2014.
  • Fenske S, Krause SC, Hassan SI, Becirovic E, Auer F, Bernard R, Kupatt C, Lange P, Ziegler T, Wotjak CT, Zhang H, Hammelmann V, Paparizos C, Biel M, Wahl-Schott CA. Sick sinus syndrome in HCN1-deficient mice. Circulation 128:2585-2594, 2013.
  • Fenske S, Mader R, Scharr A, Paparizos C, Cao-Ehlker X, Michalakis S, Shaltiel L, Weidinger M, Stieber J, Feil S, Feil R, Hofmann F, Wahl-Schott C, Biel M. HCN3 contributes to the ventricular action potential waveform in the murine heart. Circ Res 109:1015-1023, 2011.