Transregional Collaborative Research Centre 152

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P07 - Transient receptor potential channels in neurotransmitter release

This project analyses the functional impact of transient receptor potential channels (TRPC) on neurotransmitter release in neurons and neuroendocrine cells.



Taking advantage of TRPC single and compound null mutants we will study elementary mechanisms of TRPC signaling and extend these findings to complex analyses of TRPC function in synaptic transmission and organismal catecholamine homeostasis as well as in integrative functions of the hippocampus underlying memory formation.